Pūahoaho: updated information about Pharmac’s priority lists September 2025
Pharmac’s Pūahoaho Report provides the latest information about applications for medicines, vaccines, and related products that we’ve assessed for funding. Proactively releasing this information is part of our ongoing commitment to transparency.
Application priority lists
Every year we receive over 100 funding applications from health care professionals, consumer groups and suppliers. These applications include requests to fund new medicines and to widen access to medicines that we already fund.
We ask our clinical advisory committees to assess the available evidence and recommend whether we should fund, defer, or decline the applications. With their advice, we work to complete an assessment, including a health economic appraisal if required.
We apply the Factors for Consideration throughout our assessment of an application. The factors consider four areas: health need, health benefit, suitability, and costs and savings.
Factors for Consideration(external link)
Once the assessment is complete, we take the application to a quarterly internal prioritisation meeting and add applications to one of the following priority lists:
- options for investment (OFI)
- only funded if cost neutral or cost saving
- recommended for decline.
Priority lists for funding applications and previous Pūahoaho updates(external link)
Options for investment list
We rank applications on our options for investment (OFI) list from highest to lowest priority but keep these rankings confidential so that we can negotiate the best prices with suppliers.
As of 17 September 2025, there are 115 applications on the OFI.
Prioritisation activity since March
Since March’s prioritisation meeting we ranked 10 new proposals on the OFI list, and re-prioritised 23 others. Re-prioritisation can occur due to more information becoming available, or a change in an application’s Factors for Consideration in comparison to other medicines being considered for funding. Detailed descriptions of indications available on the Application Tracker.
New proposals ranked:
- Benralizumab and mepolizumab(external link) for people with severe asthma, to allow switching between treatments
- Brentuximab vedotin(external link) for previously untreated lymphoma cancer
- Durvalumab(external link) for the initial treatment of extensive stage small cell lung cancer
- Elexacaftor / tezacaftor / ivacaftor and ivacftor(external link) (Trikafta) for treatment of children aged 2-5 years with cystic fibrosis
- Fixed duration ibrutinib plus venetoxclax(external link) for a type of blood cancer called chronic lymphocytic leukaemia, for people with a TP53 mutation
- Fixed duration venetoclax with obinutuzumab(external link) for a type of blood cancer called chronic lymphocytic leukaemia, for people without a TP53 mutation
- Fluad(external link) influenza vaccine for people over 65 years
- Flucelvax(external link) influenza vaccine for people 6 months to under 65 years
- Onasemnogene abeparvovec (Zolgensma)(external link) for the treatment of spinal muscular atrophy, pre-symptomatic and type 1
- Pertussis (whooping cough) vaccine(external link) an additional dose of pertussis vaccine for children at 15 months
Applications re-ranked:
- Alitretinoin (Zematane)(external link) for severe chronic hand eczema in adults unresponsive to potent topical corticosteroids
- Atezolizumab (with chemotherapy)(external link) for the initial treatment of extensive stage small-cell lung cancer
- Benralizumab(external link) for eosinophilic asthma, widening access by lowering the minimum eosinophil count and removing the requirement for the Asthma Control Test (ACT)
- Cannabidiol (epidyoliex oral solution)(external link) for the treatment of Dravet syndrome, a severe form of epilepsy
- Daratumamab subcutaneous(external link) for the treatment of multiple myeloma, a type of blood cancer
- Influenza vaccine(external link) widening access to children up to 18 years of age
- Influenza vaccine(external link) widening access to people over 50 years of age
- Influenza vaccine(external link) widening access to an open listing
- Meningococcal vaccine(external link) for children aged 12 months
- Meningococcal vaccine(external link) for children aged 1-4 years
- Meningococcal vaccine(external link) for adolescents aged 14 years
- Meningococcal vaccine(external link) for people aged 5 to 21 years
- Meningococcal vaccine(external link) for young people aged 13 to 21 years
- Mepolizumab (Nucala)(external link) widening access for people with severe asthma by lowering the minimum eosinophil count
- Mepolizumab (Nucala)(external link) widening access for people with severe asthma by removing the requirement for the Asthma Control Test (ACT)
- Mepolizumab (Nucala)(external link) for eosinophilic asthma, widening access
- Prucalopride(external link) for chronic slow transit constipation
- Recombinant zoster vaccine (Shingrix)(external link) for people over 65 years of age who require a Shingrix catch-up at least 5 years post Zostavax
- Recombinant zoster vaccine (Shingrix)(external link) for the prevention of herpes zoster (shingles) in people aged 66-74 years (plus a catch-up programme for people aged 75 years and over)
- Rufinamide (Inovelon)(external link) for the treatment of epileptic encephalopathies, a severe form of epilepsy
- Somatropin(external link) for Prader-Willi syndrome, widening access for adults and adolescents
- Somatropin growth hormone (Genotropin)(external link) for the treatment of children born small for gestational age
- Somatropin growth hormone (Omnitrope)(external link) for the treatment of people/children with short stature due to chronic renal insufficiency
Only if cost neutral or cost saving list
If our assessment confirms an application does not provide any additional health benefit compared to treatments we already fund, it may be ranked on the only if cost-neutral or cost-saving list. We would look to fund these applications if we negotiated a deal that would be cost-neutral or cost-saving.
Prioritisation activity since March
Since March’s prioritisation meeting we ranked 18 applications on the only if cost neutral or cost saving list (detailed descriptions of indications available on the Application Tracker on our website):
- Biktarvy(external link) for the treatment of HIV
- Cabozantanib Nivolumab(external link), first line treatment for intermediate and poor prognosis kidney cancer
- Eliglustat(external link) for the treatment of type 1 and 3 Gaucher’s disease
- Entrectinib Rozlytrek(external link) for adult patients with ROS1-positive, locally advanced or metastatic non-small cell lung cancer (NSCLC)
- Faricimab (Vabysmo)(external link) for neovascular (wet) age-related macular degeneration, an eye disease
- Faricimab (Vabysmo)(external link) for diabetic macular oedema (DMO), a vision-threatening complication of diabetes
- Macitenan (Opsumit)(external link) for the treatment of portopulmonary hypertension
- Nab-paclitaxel(external link) for the treatment of cancer, contraindicated or intolerant to chemotherapy
- Nab-paclitaxel(external link) for the treatment of cancer following a reaction to paclitaxel
- Ocrelizumab subcutaneous formulation(external link) for relapsing remitting multiple sclerosis, and primary progressive multiple sclerosis
- Pembrolizumab Axitinib(external link), first line treatment of advanced kidney cancer
- Pembrolizumab Lenvatinib(external link), first line treatment of advanced kidney cancer
- Rifampicin / Isoniazid / Pyrazinamide / Ethambutol(external link) for the treatment of tuberculosis
- Sofosbuvir with velpatasvir and voxilaprevir(external link) Hepatitis C, second-line after prior direct-acting antiviral treatment (NS5A resistant)
- Sofosbuvir with velpatasvir and voxilaprevir(external link) Hepatitis C, second-line after prior direct-acting antiviral treatment
- Upadacitinib(external link) for the treatment of Crohn’s disease
- Vemurafenib and cobimetinib f(external link)or the treatment of stage three or four melanoma
- Vanzacaftor with tezacaftor and deutivacaftor (Alyftrek)(external link) treatment of cystic fibrosis, aged 6 years and older
Recommended for decline list
There are a range of reasons a funding application may be added to the recommend for decline list. Our expert clinical advisors may have recommended that the funding application be declined, or they may have provided a positive recommendation, but we’ve found:
- other more clinically preferred medicines for the same condition are now funded
- the medicine would provide no additional benefits over other treatments we already fund
- the medicine or may be harmful
- the application has been superseded by another funding application
- no company is supplying the medicine in New Zealand.
When applications are added to this list, they become inactive and we stop progressing work on the application. While applications may be listed on the decline list, they are only formally declined after public consultation to ensure we haven’t missed anything important.
More about this process: Declining inactive funding applications(external link)
If we decline an application, it means the medicine won’t be funded for the use requested at this time. It does not prevent us from reconsidering funding for the medicine in the future if new information becomes available.
Prioritisation activity since March
Since the last prioritisation meeting in March, we ranked 22 applications on the recommended for decline list (detailed descriptions of indications available on the Application Tracker):
- Atezolizumab(external link) (with chemotherapy) for advanced or metastatic triple-negative breast cancer
- Azelastine hydrochloride with fluticasone propionate(external link) for treatment of enlarged adenoids
- Bevacizumab (Avastin)(external link) for high-risk advanced ovarian cancer
- Cefuroxime(external link) for use post-cataract surgery
- Cyanocobalamin(external link) for vitamin B12 deficiency
- Dabrafenib(external link) for the treatment of melanoma
- Diflunisal(external link) for a progressive form of heart failure
- Dostarlimab-gxly (Jemperli)(external link) for the treatment of advanced or recurrent endometrial cancer
- Dupilumab (Dupixent)(external link) for chronic sinusitis with the formation of polyps in the nasal passages
- Dupilumab (Dupixent)(external link) for severe dermatitis
- Ferric carboxymaltose(external link) for the treatment of heart failure
- Naltrexone hydrochloride(external link) for opioid-induced constipation and treatment-resistant cholestasis, a blockage of bile flow from the liver to the small intestine
- Pegylated liposomal doxorubicin (Caelyx)(external link) for the treatment of advanced platinum resistant ovarian cancer
- Pegylated liposomal doxorubicin (Caelyx(external link)) for the treatment of advanced ovarian cancer (platinum sensitive / partially sensitive / intolerant)
- Pembrolizumab(external link) for use in combination with chemotherapy for cancer of the head or neck that has returned after initial treatment
- Quadrivalent Influenza virus haemagglutinin, surface antigen, inactivated, prepared in cell cultures (Flucelvax® Quad)(external link) for the prevention of influenza caused by Influenza Virus Types A and B
- Quinidine bisulphate(external link) for the treatment of Brugada syndrome, a rare heart condition
- Ribavirin(external link) for the treatment of measles
- Secukinumab(external link) for the first-line treatment of ankylosing spondylitis, a type of arthritis
- Sofosbuvir(external link) direct-acting antiviral for the treatment of hepatitis C
- Sofosbuvir(external link) for the treatment of Hepatitis C
- SARS-CoV-2 rS (Omicron XBB.1.5)(external link) COVID-19 vaccine
- Vemurafenib (Zelboraf)(external link) for the treatment of melanoma
- Ziv Aflibercept(external link) for ocular neovascularisation, an eye disease