Prednisolone acetate 1% eye drops - supply issue
PHARMAC is currently working through a supply issue with the AFT brand of prednisolone 1% eye drops – Prednisolone-AFT.
Prednisolone-AFT may be unavailable from early September 2017.
PHARMAC is working hard with AFT to ensure a quick resolution to this supply issue.
An alternate brand of the eye-drops, Allergan’s Pred Forte, has been sourced from Hong Kong as a temporary alternative during the supply issue and will be available from 1 September 2017.
The Pred Forte will be in a different pack to that previously supplied in New Zealand, but it is registered for use in New Zealand.
There are slight differences in the two different brands of prednisolone eye drops that patients should be made aware of:
Medical professionals are being encouraged to explain the key difference between the eye-drops so patients are able continue to use their medication successfully.
|Prednisolone acetate||Brand||Pack size||Pharmacode|
|Eye drops 1%||Pred Forte||5 ml OP||2528258 (from 1 September 2017)|
As there wasn’t adequate stock of Pred Forte in New Zealand or Australia, PHARMAC has worked with Allergan to source Pred Forte from Hong Kong.
The packaging is slightly different and the patient information contains slightly different information than what people may be used to.
The product is registered in New Zealand and these slight differences don’t impact on the usability or effectiveness of the eye drops. The differences in the data sheets are detailed below:
|Use in children||Safety and effectiveness of corticosteroids in children below the age of two years has not been established.||Safety and effectiveness in paediatric patients has not been established.||The use of Pred Forte eye drops in children is not listed as a contraindication in either the NZ DS or the HK package insert. As such, the use of Pred Forte eye drops in children may be considered reasonable by a prescriber so long as the benefit outweighs the risk from its use.|
|List of differences between the Hong Kong (HK) package insert and the New Zealand Data Sheet (NZ DS)|
|Sections||HK package insert||NZ DS||Comments|
|Dosage and administration||1 to 2 drops instilled into the conjunctical sac two to four times daily. During the initial 24 to 48 hours the dosage may be safely increased to 2 drops every hour. Care should be taken not to discontinue therapy prematurely.||Shake well before using. Instil one drop into the conjunctival sac two to four times daily. During the initial 24 to 48 hours, the dosing frequency may be increased if necessary. Care should be taken not to discontinue therapy prematurely.||Please note the HK package insert mentions an increased dosage of two drops, whilst the NZ DS mentions one drop. However, the NZ dose allows for an increase in dosing frequency for the short term with the objective being rapid resolution of severe and/or acute ocular inflammation.|
Where can I get more information?
If you would like more information about the change you can contact PHARMAC on firstname.lastname@example.org.
Your doctor, nurse and pharmacist will also help guide you during the changeover period.
Last updated: 14 February 2018