Compounded oral liquids containing carboxymethylcellulose: Supply issue

Supply issue Active

Due to a supply issue affecting carboxymethylcellulose, Biomed has been unable to compound a number of oral liquids.

17 April 2025 | Update

Supplies of caffeine citrate are now being affected by this issue.

Affected products

Pharmac is working closely with Biomed and other suppliers in an effort to avoid this issue affecting patients.

Biomed uses carboxymethylcellulose to thicken the following compounded oral liquids:

  • Spironolactone oral liquid 5 mg per ml, 25 ml (Pharmacode 344877)
  • Chlorothiazide oral liquid 50 mg per ml, 25 ml (Pharmacode 344818)
  • Dexamethasone oral liquid 1 mg per ml, 25 ml (Pharmacode 344842)
  • Caffeine citrate oral liquid 20 mg per ml (10 mg base per ml) (Pharmacode 461253)

Biomed is continually making and distributing these oral liquids. However, not in quantities large enough to fill all back orders. As such, supply may be inconsistent.

There is also an issue affecting the omeprazole oral liquid 1 mg per ml, 100 ml. This product used in hospitals.  Dispersible tablets have been sourced for hospitals to ensure people can continue to access omeprazole in a liquid. 

Alternatives

The tablet / capsule forms of all these products are fully funded. Although a caffeine tablet is only funded in the hospital.

We have tried a range of options to find alternative oral liquids but have not been successful.

Expected resolution

Pharmac is working with Biomed understand when supply will be able to meet demand.

Who to contact

If you have questions about this issue, email enquiry@pharmac.govt.nz

Please include as much information as you can about the product (presentation, brand, Pharmacode) and who your wholesaler is.

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