Epoetin alfa (Binocrit) inj 3,000 iu in 1 ml: Supply constraint
Supply is limited because of an increase in demand and the long lead time needed to make more of this medicine (Pharmacode: 2559781).
Affected product
There have been recent supply constraints of other strengths of this product. There may be limited access to the following product:
- Chemical: Epoetin alfa
- Presentation: Inj 3,000 iu in 1 ml, syringe
- Brand: Binocrit
- Pharmacode: 2559781
- Subsidy: $150.00
- Measure / Qty: per 6
Epoetin alfa Schedule listing(external link)
Alternatives
All other strengths of epoetin alfa remain available.
Advice from the supplier
The supplier has previously written to health care professionals with the following table and dosing advice.
|
Binocrit dose strength |
Filled volume |
Total content of active ingredient |
Concentration |
|---|---|---|---|
|
1000 IU |
0.5 ml |
8.4 mcg |
16.8 mcg/ml |
|
2000 IU |
1 ml |
16.8 mcg |
16.8 mcg/ml |
|
3000 IU |
0.3 ml |
25.2 mcg |
84 mcg/ml |
|
4000 IU |
0.4 ml |
33.6 mcg |
84 mcg/ml |
|
5000 IU |
0.5 ml |
42 mcg |
84 mcg/ml |
|
6000 IU |
0.6 ml |
50.4 mcg |
84 mcg/ml |
|
8000 IU |
0.8 ml |
67.2 mcg |
84 mcg/ml |
|
10,000 IU |
1 ml |
84 mcg |
84 mcg/ml |
|
40,000 IU |
1 ml |
336 mcg |
336 mcg/ml |
The treating physician is required to assess the risk-benefit of switching to an alternative dose strength to ensure treatment remains uninterrupted.
Dosing limit
Please note, for subcutaneous administration, dosing of a maximum volume of 1 mL should not be exceeded at any one injection site.
In case of larger volumes, the injection should be divided between more than one site.
Resupply
We are working closely with the supplier to understand when this strength will be available again.
The supplier anticipates further supply limitations for Binocrit over the coming months.
Who to contact
If you have questions about this issue, email enquiry@pharmac.govt.nz
Please include as much information as you can about the product (presentation, brand, pharmacode) and who your wholesaler is.
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