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2012-04-03 NPPA Outcome report cumulative for March and April

Panels Date from Date to Abbreviation UCC UA HPC Pathway Approved Declined Pathway HPC HPC HPC HPC HPC NPPA 1/03/2012 30/04/2012 Explanation Unusual Clinical Circumstances Urgent Assessment Hospital Pharmaceuticals in the Community UCC/UA/HPC/Other 71 8 Drug moxifloxacin valganciclovir valganciclovir valganciclovir voriconazole Indication mycoplasma genitalium infection Crohn's diease, Cytomegalovirus induced haemophagocytic lymphohistiocytosis Kidney Transplant, Prophylaxis of CMV Acute Myeloid Leukaemia, CMV viraemia, post bone marrow transplant, secondary pancytopenia Acute Lymphoblastic Leukaemia, allogeneic sibling stem cell transplant, CT proven chest infection, pulmonary embolism Acute Lymphoblastic Leukaemia, aspergillus grown in sputum, Aspergilus lung infection in neutrophenic patient, intensive chemotherapy Atrial fibrillation, Invasive Pulmonary Aspergillosis diabetes type 2, mucositus, supraglottic tumour hypercalcaemia, primary hyperparathyroidism infected prosthetic knee joint, vancomycin resistant staphylococcus aureus complex congenital heart disease, mediastinitis MRSA, respiratory infection, tracheobronchomalacia enterococcus faecalis infection, multidrug resistant staph infection multidrug-resistant streptococcus pneumoniae pneumonia bacteraemia, enterococcus faecalis infection post pancreatectomy for cancer recurrent respiratory papillomatosis risk of pre-term labour global development delay, Intractable Epilepsy, visual impairment gingivostomatitis, immunosuppressed patient, Recurrent herpes simplex Acute Myeloid Leukaemia AML, Invasive Pulmonary Aspergillosis, metastatic breast oral mucositis, squamous cell carcinoma left tonsil, undergoing chemotherapy and radiotherapy hypoglycaemia, Insulinoma epilepsy Blackfan-Diamond Syndrome, transfusion dependent iron overload Result Approved Approved Approved Approved Approved

HPC HPC HPC HPC HPC HPC HPC HPC HPC HPC HPC HPC HPC HPC HPC HPC HPC Other UA

voriconazole voriconazole calcium phosphate cinacalcet daptomycin linezolid linezolid moxifloxacin moxifloxacin octreotide papillomavirus vaccine progesterone pessary pyridoxal 5-phosphate valaciclovir voriconazole calcium phosphate diazoxide oxcarbazepine deferasirox

Approved Approved Approved Approved Approved Approved Approved Approved Approved Approved Approved Approved Approved Approved Approved Approved Approved Approved Approved


UA UCC UCC UCC

diazoxide amiloride androstanolone androstanolone

Genetic testing re undiagnosed syndrome, Recurrent hypoglycaemia secondary to hyperinsulinism hypertension, primary hyperaldosteronism microphallus, Partial Androgen Insensitivity Syndrome microphallus, Partial Androgen Insensitivity Syndrome autosomal recessive polycystic kidney disease, bone marrow fibrosis, congenital hepatic fibrosis, End stage renal failure, failure to thrive, hypersplenism, oesophageal varicies, Portal Hypertension, Severe hyperthyroidism Refractory ITP bulbar palsy, carnitine deficiency, global development delay, Incontinence, refractory epilepsy, respiratory infection acute pancreatitis secondary to sunitinib low grade malignant nerve sheath tumour, neuropathic pain risk of pre-term labour, ovarian torsion angiosarcoma of the pericardium pustular psoriasis Cushing's Disease, hypercorticolism heart failure, hyperkalaemia, MELAS, Pleural Effusion basilar artery occlusion, No resolution on warfarin, recurrent stroke syndromes IgA multiple myeloma, bilateral diaphramatic paralysis secondary to bortezomib inadequate nutrition, primary biliary cirrhosis Cystic fibrosis, pancreatic insufficiency Fistulating Anus, pain, rectal carcinoma diffuse large B-cell lymphoma, hepatitis B core antigen positive anxiety, Central sensitisation syndrome, chronic abdominal pain, Chronic Nausea, Chronic severe constipation, Gastrooesophageal reflux, gastrostomy feeding, Past history of rheumatic fever Refractory giardiasis Refractory giardiasis cardiac arrhythmias, Hypertrophic cardiomyopathy Chest Pain, neuropathic pain in pregnancy, SLE adrenal cortical carcinoma congenital ichthyosis, preterm malignant pleural mesothelioma diabetes, essential thrombocythaemia, severe vascular ulceration essential thrombocythaemia, Heart failure on anagrelide, Non-responsive to anagrelide, Skin ulcers on hydroxyurea essential thrombocythaemia, polycythaemia vera

Approved Approved Approved Approved

UCC

cinacalcet

Approved

UCC UCC UCC UCC UCC UCC UCC UCC UCC UCC UCC UCC UCC UA UA

eltrombopag l-carnitine pazopanib pregabalin progesterone sunitinib acitretin oral suspension cabergoline co-enzyme q10 enoxaparin lenalidomide oral feed 1.5kcal/ml (Fortisip) pancreatin ketamine lamivudine

Approved Approved Approved Approved Approved Approved Approved Approved Approved Approved Approved Approved Approved Approved Approved

UA

macrogol

Approved

UA UA UA UA UA UA UA UA UA UA

mepacrine mepacrine mexiletine mexiletine mitotane paraffin liquid and white soft paraffin pemetrexed pipobroman pipobroman pipobroman

Approved Approved Approved Approved Approved Approved Approved Approved Approved Approved


UA UA UA UA UA UA UA UA UA UA UA UA UA UA UA UA UCC/UA UCC/UA UCC/UA UCC/UA UCC/UA UCC/UA UCC/UA UCC/UA

spiramycin cisapride dantrolene desmopressin tablet desmopressin tablet flucytosine l-carnitine methylphenidate extended release nicorandil nilotinib oxaliplatin propranolol propranolol slow sodium sodium chloride solution vitamin b12 capsule (cyanocobalamin) fluoxetine (Prozac) food thickener (Nutilis 900) hydroxybutyrate lenalidomide naproxen/esomeprazole pegasparaginase pegasparaginase pegasparaginase

foetal toxoplasmosis infection, maternal toxoplasmosis cerebral palsy, constipation, enteral feeds, pain Motor Neurone disease, spasm, spasticity, spinal myelopathy central diabetes insipidus, Langerhans cell histiocytosis addictive behaviour, diabetes insipidus, Langerhans cell histiocytosis cryptococcal infection methylmalonic acidemia narcolepsy refractory angina, ischaemic heart disease CML, intolerant to dasatinib, resistant to imatinib metastatic small bowel adenocarcinoma cardiac arrhythmias, Hypertrophic cardiomyopathy infantile haemangioma, laryngomaiacia hyponatraemia secondary to SIADH Cystic fibrosis, meconium ileus at birth methylmalonic acidemia Depression chronic dysphagia, spastic quadriplegia Alternating hemiplegia of childhood, glucose transporter abnormality Multiple Myeloma Gastric reflux, Osteoarthritis Acute Lymphoblastic Leukaemia Acute Lymphoblastic Leukaemia Lymphoblastic T-cell lymphoma

Approved Approved Approved Approved Approved Approved Approved Approved Approved Approved Approved Approved Approved Approved Approved Approved Declined Declined Declined Declined Declined Declined Declined Declined

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Title

NPPA Outcome report cumulative for March and April

Abstract

2012-04-03 NPPA Outcome report cumulative for March and April Panels Date from Date to Abbreviation UCC UA HPC Pathway Approved Declined Pathway HPC HPC HPC HPC HPC NPPA 1/03/2012 30/04/2012 Explanation Unusual Clinical Circumstances Urgent Assessment Hospital Pharmaceuticals in the…

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