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2007 / 04 / 13

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Appendix One: Relevant minutes of clinical advisory committees meetings since mid 2006 (8 pages, 164 KB)
2007/04/13
CAC

PTAC further considered trastuzumab in August 2006, and then the cancer treatments subcommittee of PTAC (CaTSoP) considered the FinHer study in November 2006. Subsequently PTAC have discussed this…

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Appendix Six: Clinical data (14 pages, 511 KB)
2007/04/13

1. Efficacy of sequential and concurrent treatments Key to graphic: Ö statistically significant improvement in disease-free survival (DFS) ´ no statistically significant improvement in DFS ? results awaited 2. Treatment regimens and available trial data To…

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Appendix Two: Rapid update of TAR 75 for HERA 23 month follow-up information (2 pages, 124 KB)
2007/04/13

Updated Clinical Information – 12 months trastuzumab sequential regimen The cost-utility analysis for 12 months sequential trastuzumab treatment has not been updated to include the new evidence…

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Comparison of eligible patient pool and treatment regimen 12 months sequential treatment (3 pages, 63 KB)
2007/04/13

Eligible patient population 9 weeks concurrent treatment Eligible patients were those presenting with HER-2 positive early breast cancer, with acceptable heart function (assumes some patients excluded from treatment…

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Technology Assessment Report No. 75, with supplementary analysis 75b (66 pages, 566 KB)
2007/04/13

Trastuzumab (Herceptin) in HER-2 positive early stage primary breast cancer Part 1: 12-month sequential trastuzumab treatment (“Trastuzumab (Herceptin) in HER-2 positive early breast cancer ”), August 2006 Part 2: 9 week…

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