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Drug cost by Therapeutic Group (excluding compounds)

Jun 99 Alimentary Tract and Metabolism $82,188,739 Blood and Blood Forming Organs $32,581,733 Cardiovascular System $82,697,631 Dermatologicals $25,439,897 Genito-Urinary System $15,422,448 Hormone Preparations - Systemic excluding Contraceptive Hormones $23,504,831 Infections - Agents for Systemic Use $43,783,342 Musculo-Skeletal System $14,169,797 Nervous System $89,457,456 Oncology Agents and Immunosuppressants $17,321,696 Respiratory System and Allergies $74,727,067 Sensory Organs $6,652,279 Special Foods $6,703,868 $514,650,783 Year Ending Jun 00 $91,683,115 $47,161,709 $74,505,439 $22,255,908 $13,863,190 $26,029,317 $39,313,031 $12,019,454 $101,180,674 $16,513,623 $68,774,951 $6,595,275 $6,473,013 $526,368,701 Jun 01 $100,577,446 $57,280,122 $68,666,929 $21,372,472 $13,656,401 $28,100,665 $33,910,214 $7,906,216 $105,177,878 $20,437,934 $62,319,707 $7,037,974 $7,645,326 $534,089,284 Jun 02 $104,589,808 $53,921,283 $58,755,364 $21,774,163 $13,405,975 $29,677,090 $32,358,513 $7,048,710 $117,698,356 $21,576,563 $60,881,626 $7,520,110 $8,408,966 $537,616,529 Jun 03 $114,379,234 $59,110,616 $61,185,573 $19,967,574 $13,005,991 $29,543,976 $32,784,011 $9,108,540 $129,649,839 $27,771,971 $60,320,498 $8,838,111 $9,117,426 $574,783,359

Alimentary Tract and Metabolism

Year Ending Main Antidiarrhoeals Main Anti-ulcerants Main Diabetes Main Diabetes Management Main Vitamins Rest Remainder Jun 99 $7,442,115 $29,018,532 $17,206,848 $12,641,985 $3,633,302 $12,245,957 $82,188,739 Jun 00 $7,557,108 $36,076,274 $18,021,780 $13,990,631 $3,949,351 $12,087,971 Jun 01 $8,432,768 $42,726,469 $17,118,611 $16,154,033 $4,117,224 $12,028,341 Jun 02 $8,717,462 $44,108,946 $18,585,203 $18,129,334 $4,058,984 $10,989,879 Jun 03 $9,186,469 $52,189,513 $18,951,091 $19,428,831 $3,957,211 $10,666,118

$91,683,115 $100,577,446 $104,589,808 $114,379,234

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Blood and Blood Forming Organs

Year Ending Main Antianaemics Main Antifibrinolytics, Haemostatics and Local Sclerosants Main Antithrombotic Agents Main Fluids and Electrolytes Main Modifying Agents Lipid Jun 99 $3,023,991 $330,330 $2,729,422 $2,845,152 $23,652,838 $32,581,733 Jun 00 $4,014,170 $431,653 $3,007,944 $2,500,676 $37,207,267 $47,161,709 Jun 01 $4,909,611 $526,551 $3,483,620 $3,587,529 $44,772,810 $57,280,122 Jun 02 $5,340,542 $517,261 $3,953,590 $3,656,380 $40,453,510 $53,921,283 Jun 03 $4,668,532 $670,742 $4,237,763 $3,461,444 $46,072,135 $59,110,616

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Cardiovascular System

Year Ending Main Agents affecting the Renin-Angiotensin system Main Alpha Adrenoceptor Blockers Main Anti-arrythmics Main Adrenoceptor Blockers Beta Main Calcium Channel Blockers Rest Remainder Jun 99 $26,730,102 $6,675,545 $4,444,592 $11,713,497 $24,902,091 $8,231,805 $82,697,631 Jun 00 $27,199,511 $7,805,725 $4,771,456 $8,955,033 $17,545,583 $8,228,131 $74,505,439 Jun 01 $27,224,336 $7,712,053 $4,973,598 $7,987,020 $15,582,894 $5,187,029 $68,666,929 Jun 02 $21,357,029 $5,266,183 $5,135,784 $7,972,065 $13,885,554 $5,138,748 $58,755,364 Jun 03 $23,027,544 $4,526,811 $5,189,526 $9,231,486 $13,770,652 $5,439,555 $61,185,573

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Dermatologicals

Year Ending Main Anti-acne Preparations Main Antibacterials Topical Main Corticosteroids Topical Main Emollients and Barrier Creams Main Psoriasis and Eczema Preparations Rest Remainder Jun 99 $8,843,867 $1,385,514 $8,004,686 $1,353,433 $2,639,870 $3,212,527 $25,439,897 Jun 00 $6,876,300 $1,429,903 $7,925,893 $1,107,005 $2,404,635 $2,512,171 $22,255,908 Jun 01 $7,220,981 $1,406,952 $6,848,399 $997,180 $2,397,923 $2,501,036 $21,372,472 Jun 02 $7,704,576 $1,424,141 $6,662,428 $1,098,052 $2,390,677 $2,494,290 $21,774,163 Jun 03 $5,662,052 $1,407,247 $6,725,600 $1,151,786 $2,496,467 $2,524,421 $19,967,574

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Genito-Urinary System

Year Ending Main Anti-androgen oral contraceptives Main Contraceptives - hormonal Main Contraceptives - hormonal, Non-interchangeable Main Contraceptives - non-hormonal Main Urinary Agents Rest Remainder Jun 99 $893,187 $9,323,846 $184,511 $1,973,527 $1,087,673 $1,959,704 $15,422,448 Jun 00 $1,144,799 $8,173,267 $628,478 $1,922,121 $575,697 $1,418,828 $13,863,190 Jun 01 $1,311,390 $7,998,076 $730,349 $1,867,133 $559,876 $1,189,577 $13,656,401 Jun 02 $1,182,557 $7,752,103 $830,379 $1,647,437 $568,767 $1,424,733 $13,405,975 Jun 03 $842,906 $7,632,316 $972,008 $1,581,101 $595,605 $1,382,054 $13,005,991

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Hormone Preparations - Systemic excluding Contraceptive Hormones

Year Ending Main Calcium Homeostasis Main Corticosteroids and Related Agents for Systemic Use Main Hormone Replacement Therapy - Systemic Main Hormones Non Contraceptive Sex Main Trophic Hormones Rest Remainder Jun 99 $1,716,406 $1,824,402 $6,975,272 $3,640,617 $5,549,697 $3,798,436 $23,504,831 Jun 00 $2,730,232 $2,015,829 $7,119,827 $3,947,910 $6,550,700 $3,664,819 $26,029,317 Jun 01 $4,108,534 $1,598,342 $6,917,491 $4,306,589 $7,186,365 $3,983,344 $28,100,665 Jun 02 $5,694,185 $1,966,757 $6,632,638 $3,647,552 $7,729,180 $4,006,778 $29,677,090 Jun 03 $7,699,420 $2,181,106 $3,832,992 $3,203,770 $8,481,922 $4,144,767 $29,543,976

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Infections - Agents for Systemic Use

Year Ending Main Antibacterials Main Antifungals Main Antiretrovirals Main Antivirals Main Urinary Tract Infections Rest Remainder Jun 99 $28,253,286 $5,168,367 $3,522,621 $4,167,261 $1,060,316 $1,611,490 $43,783,342 Jun 00 $23,109,218 $6,160,795 $4,615,898 $3,008,579 $957,792 $1,460,748 $39,313,031 Jun 01 $16,234,941 $7,507,448 $5,254,701 $2,517,091 $958,441 $1,437,592 $33,910,214 Jun 02 $15,365,037 $7,721,583 $5,701,308 $1,191,896 $983,894 $1,394,795 $32,358,513 Jun 03 $14,549,217 $7,930,060 $6,418,012 $1,451,877 $1,014,316 $1,420,528 $32,784,011

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Musculo-Skeletal System

Year Ending Main Anti-inflammatory Non Steroidal Drugs (NSAIDs) Main Antirheumatoid Agents Main Corticosteroids - Injectables Main Hyperuricaemia and Antigout Main Muscle Relaxants Rest Remainder Jun 99 $9,429,039 $336,367 $768,070 $1,432,372 $2,089,242 $114,708 $14,169,797 Jun 00 $7,274,592 $305,005 $746,242 $1,459,483 $2,117,416 $116,716 $12,019,454 Jun 01 $5,453,347 $297,200 $663,845 $727,134 $656,488 $108,202 $7,906,216 Jun 02 $4,773,055 $481,331 $460,175 $587,684 $646,713 $99,753 $7,048,710 Jun 03 $4,740,915 $2,230,313 $451,070 $923,801 $658,222 $104,220 $9,108,540

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Nervous System

Year Ending Main Analgesics Main Antidepressants Main Anti-Epilepsy Drugs Main Antimigraine Preparations Main Antipsychotics Rest Remainder Jun 99 $13,729,099 $31,868,040 $13,743,535 $7,306,986 $10,515,006 $12,294,790 Jun 00 $13,454,449 $28,603,225 $15,171,503 $8,258,004 $23,906,733 $11,786,759 Jun 01 $13,671,299 $24,992,295 $15,977,119 $9,629,670 $30,144,865 $10,762,630 Jun 02 $14,667,033 $28,054,262 $17,497,161 $10,500,428 $36,673,284 $10,306,189 Jun 03 $15,547,437 $32,740,982 $19,009,181 $11,229,678 $40,821,937 $10,300,625

$89,457,456 $101,180,674 $105,177,878 $117,698,356 $129,649,839

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Oncology Agents and Immunosuppressants

Year Ending Main Chemotherapeutic Agents Main Endocrine Therapy Main Immunosuppressants Jun 99 $1,169,890 $4,459,797 $11,692,010 $17,321,696 Jun 00 $1,212,941 $3,332,458 $11,968,224 $16,513,623 Jun 01 $1,341,277 $3,405,691 $15,690,966 $20,437,934 Jun 02 $1,347,899 $4,088,416 $16,140,248 $21,576,563 Jun 03 $5,326,454 $4,424,720 $18,020,797 $27,771,971

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Respiratory System and Allergies

Year Ending Main Inhaled beta-adrenoceptor agonist and anticholinergic agents - mdi Main Inhaled beta-adrenoceptor agonists - long acting inhalers Main Inhaled beta-adrenoceptor agonists - metered dose inhalers Main Inhaled corticosteroids - breath activated devices Main Inhaled corticosteroids - metered dose inhalers Rest Remainder Jun 99 $1,746,411 $2,613,794 $4,592,312 $15,255,228 $24,946,646 $25,572,677 $74,727,067 Jun 00 $2,171,127 $3,344,915 $4,670,665 $15,584,787 $19,706,977 $23,296,479 $68,774,951 Jun 01 $2,533,667 $4,209,326 $4,659,012 $14,164,229 $18,695,585 $18,057,889 $62,319,707 Jun 02 $2,832,031 $5,952,999 $7,813,125 $5,907,185 $21,905,489 $16,470,798 $60,881,626 Jun 03 $3,104,551 $9,987,468 $8,086,529 $4,401,188 $20,689,721 $14,051,041 $60,320,498

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Sensory Organs

Year Ending Main Ear/Eye Preparations Main Preparations Ear Main Preparations Eye Jun 99 $719,931 $220,261 $5,712,088 $6,652,279 Jun 00 $691,957 $205,527 $5,697,791 $6,595,275 Jun 01 $664,340 $198,307 $6,175,327 $7,037,974 Jun 02 $650,146 $199,978 $6,669,986 $7,520,110 Jun 03 $549,924 $190,095 $8,098,092 $8,838,111

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Special Foods

Year Ending Main Foods used for PKU and other inborn errors of metabolism Main Gluten Free Foods Main Formulae Infant Main Nutrient Modules Main Supplements/Complete Diet (nasogastric/ gastronomy tube feed) Oral Rest Remainder Jun 99 $1,334,726 $691,526 $379,749 $1,121,612 $3,091,155 $85,101 $6,703,868 Jun 00 $1,749,790 $144,023 $450,068 $220,890 $3,809,143 $99,100 $6,473,013 Jun 01 $1,834,835 $140,442 $544,210 $214,973 $4,779,823 $131,042 $7,645,326 Jun 02 $2,017,362 $157,858 $560,161 $215,238 $5,310,011 $148,337 $8,408,966 Jun 03 $2,122,395 $156,643 $687,415 $209,801 $5,794,190 $146,983 $9,117,426

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Prescriptions by Therapeutic Group (excluding compounds)

Year Ending Alimentary Tract and Metabolism Blood and Blood Forming Organs Cardiovascular System Dermatologicals Genito-Urinary System Hormone Preparations - Systemic excluding Contraceptive Hormones Infections - Agents for Systemic Use Musculo-Skeletal System Nervous System Oncology Agents and Immunosuppressants Respiratory System and Allergies Sensory Organs Special Foods Jun 99 2,510,504 1,173,093 3,004,202 1,703,555 955,463 997,623 3,581,778 1,151,220 3,822,008 89,973 2,401,377 634,822 43,673 22,069,291 Jun 00 2,536,663 1,251,156 3,039,281 1,638,079 894,448 1,007,788 3,284,619 1,068,025 3,868,266 94,505 2,437,084 613,996 42,526 21,776,436 Jun 01 2,656,206 1,332,410 3,121,785 1,509,774 896,701 1,051,791 2,945,043 982,729 3,948,108 100,208 2,283,152 607,690 41,134 21,476,731 Jun 02 2,772,452 1,455,913 3,225,414 1,602,452 897,668 1,089,784 2,962,990 966,324 4,117,965 106,519 2,332,890 612,113 47,636 22,190,120 Jun 03 2,924,000 1,691,063 3,394,887 1,644,063 863,143 975,870 2,861,981 968,583 4,238,357 110,342 2,209,006 601,806 36,955 22,520,056

Alimentary Tract and Metabolism

Year Ending Main Antidiarrhoeals Main Anti-ulcerants Main Diabetes Main Diabetes Management Main Vitamins Rest Remainder Jun 99 150,398 641,628 380,865 174,161 179,022 984,430 2,510,504 Jun 00 155,723 667,935 403,874 184,611 193,495 931,025 2,536,663 Jun 01 170,371 724,781 413,230 201,209 215,580 931,035 2,656,206 Jun 02 182,367 807,689 444,120 218,339 238,428 881,509 2,772,452 Jun 03 190,173 901,049 472,432 227,455 267,339 865,552 2,924,000

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Blood and Blood Forming Organs

Year Ending Main Antianaemics Main Antifibrinolytics, Haemostatics and Local Sclerosants Main Antithrombotic Agents Main Fluids and Electrolytes Main Modifying Agents Lipid Jun 99 203,349 6,418 510,459 172,606 280,261 1,173,093 Jun 00 195,364 7,951 506,179 168,276 373,386 1,251,156 Jun 01 194,569 9,953 498,544 165,488 463,856 1,332,410 Jun 02 211,568 15,356 497,575 170,611 560,803 1,455,913 Jun 03 235,531 21,778 495,925 175,254 762,575 1,691,063

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Cardiovascular System

Year Ending Main Agents affecting the Renin-Angiotensin system Main Alpha Adrenoceptor Blockers Main Anti-arrythmics Main Adrenoceptor Blockers Beta Main Calcium Channel Blockers Rest Remainder Jun 99 764,558 147,383 181,256 529,467 448,632 932,906 3,004,202 Jun 00 778,917 163,182 170,551 547,322 454,216 925,093 3,039,281 Jun 01 840,299 169,173 162,998 574,955 469,411 904,949 3,121,785 Jun 02 889,578 163,939 156,210 619,761 490,395 905,531 3,225,414 Jun 03 959,048 166,403 150,474 669,418 533,617 915,927 3,394,887

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Dermatologicals

Year Ending Main Anti-acne Preparations Main Antibacterials Topical Main Corticosteroids Topical Main Emollients and Barrier Creams Main Psoriasis and Eczema Preparations Rest Remainder Jun 99 26,244 189,261 777,413 247,507 112,889 350,241 1,703,555 Jun 00 27,746 198,524 769,802 245,131 99,693 297,183 1,638,079 Jun 01 29,556 199,069 715,143 217,529 70,957 277,520 1,509,774 Jun 02 29,804 204,894 752,717 249,157 88,681 277,199 1,602,452 Jun 03 24,186 202,412 777,369 273,134 92,835 274,127 1,644,063

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Genito-Urinary System

Year Ending Main Anti-androgen oral contraceptives Main Contraceptives - hormonal Main Contraceptives - hormonal, Non-interchangeable Main Contraceptives - non-hormonal Main Urinary Agents Rest Remainder Jun 99 55,822 561,919 15,509 109,479 74,756 137,978 955,463 Jun 00 64,840 489,603 43,318 109,461 68,841 118,385 894,448 Jun 01 70,094 484,359 49,043 112,144 66,094 114,967 896,701 Jun 02 78,846 472,484 55,740 110,809 66,612 113,177 897,668 Jun 03 54,769 455,429 63,292 110,435 68,319 110,899 863,143

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Hormone Preparations - Systemic excluding Contraceptive Hormones

Year Ending Main Calcium Homeostasis Main Corticosteroids and Related Agents for Systemic Use Main Hormone Replacement Therapy - Systemic Main Hormones Non Contraceptive Sex Main Trophic Hormones Rest Remainder Jun 99 25,281 330,233 390,871 12,202 3,126 235,910 997,623 Jun 00 39,577 331,689 388,523 13,181 4,170 230,648 1,007,788 Jun 01 58,889 335,662 393,617 14,342 5,087 244,194 1,051,791 Jun 02 79,184 363,636 376,072 14,670 6,124 250,098 1,089,784 Jun 03 104,077 364,409 234,183 14,327 6,968 251,906 975,870

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Infections - Agents for Systemic Use

Year Ending Main Antibacterials Main Antifungals Main Antiretrovirals Main Antivirals Main Urinary Tract Infections Rest Remainder Jun 99 3,276,799 45,344 3,515 39,782 110,842 105,496 3,581,778 Jun 00 2,982,305 49,955 3,973 43,321 113,015 92,050 3,284,619 Jun 01 2,625,948 56,201 4,451 44,278 122,333 91,832 2,945,043 Jun 02 2,641,329 58,110 4,862 39,521 129,507 89,661 2,962,990 Jun 03 2,537,376 58,539 5,208 42,411 129,994 88,453 2,861,981

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Musculo-Skeletal System

Year Ending Main Anti-inflammatory Non Steroidal Drugs (NSAIDs) Main Antirheumatoid Agents Main Corticosteroids - Injectables Main Hyperuricaemia and Antigout Main Muscle Relaxants Rest Remainder Jun 99 843,804 2,788 21,507 176,167 105,219 1,735 1,151,220 Jun 00 767,538 2,559 20,497 176,958 98,769 1,704 1,068,025 Jun 01 721,101 2,352 18,891 150,267 88,492 1,626 982,729 Jun 02 709,774 2,707 15,992 149,240 87,203 1,408 966,324 Jun 03 701,751 5,370 15,543 159,066 85,456 1,397 968,583

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Nervous System

Year Ending Main Analgesics Main Antidepressants Main Anti-Epilepsy Drugs Main Antimigraine Preparations Main Antipsychotics Rest Remainder Jun 99 1,603,250 614,832 270,916 101,960 224,891 1,006,159 3,822,008 Jun 00 1,622,669 639,797 271,974 102,667 250,400 980,759 3,868,266 Jun 01 1,655,166 671,951 277,691 104,359 252,411 986,530 3,948,108 Jun 02 1,741,963 701,630 286,046 105,065 256,780 1,026,481 4,117,965 Jun 03 1,773,657 752,544 291,558 103,427 269,855 1,047,316 4,238,357

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Oncology Agents and Immunosuppressants

Year Ending Main Chemotherapeutic Agents Main Endocrine Therapy Main Immunosuppressants Jun 99 35,283 32,751 21,939 89,973 Jun 00 37,647 32,822 24,036 94,505 Jun 01 41,267 32,993 25,948 100,208 Jun 02 45,793 33,142 27,584 106,519 Jun 03 48,447 32,520 29,375 110,342

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Respiratory System and Allergies

Year Ending Main Inhaled beta-adrenoceptor agonist and anticholinergic agents - mdi Main Inhaled beta-adrenoceptor agonists - long acting inhalers Main Inhaled beta-adrenoceptor agonists - metered dose inhalers Main Inhaled corticosteroids - breath activated devices Main Inhaled corticosteroids - metered dose inhalers Rest Remainder Jun 99 58,391 28,001 505,884 179,075 414,616 1,215,410 2,401,377 Jun 00 74,274 34,194 511,962 184,108 420,490 1,212,056 2,437,084 Jun 01 84,627 44,212 503,351 176,299 428,672 1,045,991 2,283,152 Jun 02 92,356 74,452 559,337 134,674 472,894 999,177 2,332,890 Jun 03 98,220 103,070 566,873 108,588 479,542 852,713 2,209,006

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Sensory Organs

Year Ending Main Ear/Eye Preparations Main Preparations Ear Main Preparations Eye Jun 99 135,884 34,526 464,412 634,822 Jun 00 129,767 32,675 451,554 613,996 Jun 01 124,858 31,639 451,193 607,690 Jun 02 122,700 31,313 458,100 612,113 Jun 03 106,994 30,291 464,521 601,806

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Special Foods

Year Ending Main Foods used for PKU and other inborn errors of metabolism Main Gluten Free Foods Main Formulae Infant Main Nutrient Modules Main Supplements/Complete Diet (nasogastric/ gastronomy tube feed) Oral Rest Remainder Jun 99 736 7,162 2,613 7,871 24,421 870 43,673 Jun 00 794 5,044 2,152 2,017 31,365 1,154 42,526 Jun 01 1,011 4,359 2,103 1,458 30,844 1,359 41,134 Jun 02 1,226 4,913 4,548 1,542 33,116 2,291 47,636 Jun 03 720 4,326 1,788 1,113 27,630 1,378 36,955

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Investment by Therapeutic Groups

$574,783,359 for the year ending Jun 03

Alimentary Tract and Metabolism $114.38M ( 19.90 % ) Cardiovascular System $61.19M ( 10.64 % )

Respiratory System and Allergies $60.32M ( 10.49 % ) Nervous System $129.65M ( 22.56 % )

Blood and Blood Forming Organs $59.11M ( 10.28 % )

Dermatologicals $19.97M ( 3.47 % ) Other (GUS,M-SS,SO,SF) $40.07M ( 6.97 % ) Oncology Agents and Immunosuppressants $27.77M ( 4.83 % ) Infections - Agents for Systemic Use $32.78M ( 5.70 % ) Hormone Preparations - Systemic excluding Contraceptive Hormones $29.54M ( 5.14 % )

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Alimentary Tract and Metabolism

$114,379,234 for the year ending Jun 03

Diabetes $18.95M ( 16.57 % ) Antidiarrhoeals $9.19M ( 8.03 % ) Vitamins $3.96M ( 3.46 % )

Remainder $10.67M ( 9.33 % )

Diabetes Management $19.43M ( 16.99 % )

Anti-ulcerants $52.19M ( 45.63 % )

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Blood and Blood Forming Organs

$59,110,616 for the year ending Jun 03

Antianaemics $4.67M ( 7.90 % ) Antithrombotic Agents $4.24M ( 7.17 % )

Fluids and Electrolytes $3.46M ( 5.86 % ) Antifibrinolytics, Haemostatics and Local Sclerosants $0.67M ( 1.13 % )

Lipid Modifying Agents $46.07M ( 77.94 % )

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Cardiovascular System

$61,185,573 for the year ending Jun 03

Alpha Adrenoceptor Blockers $4.53M ( 7.40 % ) Remainder $5.44M ( 8.89 % )

Beta Adrenoceptor Blockers $9.23M ( 15.09 % )

Anti-arrythmics $5.19M ( 8.48 % )

Calcium Channel Blockers $13.77M ( 22.51 % )

Agents affecting the Renin-Angiotensin system $23.03M ( 37.64 % )

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Dermatologicals

$19,967,574 for the year ending Jun 03

Psoriasis and Eczema Preparations $2.50M ( 12.50 % )

Anti-acne Preparations $5.66M ( 28.36 % )

Remainder $2.52M ( 12.64 % )

Antibacterials Topical $1.41M ( 7.05 % ) Emollients and Barrier Creams $1.15M ( 5.77 % )

Corticosteroids Topical $6.73M ( 33.68 % )

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Genito-Urinary System

$13,005,991 for the year ending Jun 03

Contraceptives - hormonal, Non-interchangeable $0.97M ( 7.47 % ) Contraceptives - non-hormonal $1.58M ( 12.16 % ) Anti-androgen oral contraceptives $0.84M ( 6.48 % ) Urinary Agents $0.60M ( 4.58 % )

Remainder $1.38M ( 10.63 % )

Contraceptives - hormonal $7.63M ( 58.68 % )

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Hormone Preparations - Systemic excluding Contraceptive Hormones

$29,543,976 for the year ending Jun 03

Corticosteroids and Related Agents for Systemic Use $2.18M ( 7.38 % ) Remainder $4.14M ( 14.03 % ) Sex Hormones Non Contraceptive $3.20M ( 10.84 % )

Hormone Replacement Therapy - Systemic $3.83M ( 12.97 % )

Trophic Hormones $8.48M ( 28.71 % )

Calcium Homeostasis $7.70M ( 26.06 % )

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Infections - Agents for Systemic Use

$32,784,011 for the year ending Jun 03

Antiretrovirals $6.42M ( 19.58 % )

Antifungals $7.93M ( 24.19 % ) Remainder $1.42M ( 4.33 % ) Antivirals $1.45M ( 4.43 % )

Urinary Tract Infections $1.01M ( 3.09 % )

Antibacterials $14.55M ( 44.38 % )

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Musculo-Skeletal System

$9,108,540 for the year ending Jun 03

Hyperuricaemia and Antigout $0.92M ( 10.14 % ) Antirheumatoid Agents $2.23M ( 24.49 % ) Corticosteroids - Injectables $0.45M ( 4.95 % ) Remainder $0.10M ( 1.14 % )

Muscle Relaxants $0.66M ( 7.23 % )

Anti-inflammatory Non Steroidal Drugs (NSAIDs) $4.74M ( 52.05 % )

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Nervous System

$129,649,839 for the year ending Jun 03

Analgesics $15.55M ( 11.99 % ) Antimigraine Preparations $11.23M ( 8.66 % ) Anti-Epilepsy Drugs $19.01M ( 14.66 % )

Remainder $10.30M ( 7.94 % )

Antidepressants $32.74M ( 25.25 % )

Antipsychotics $40.82M ( 31.49 % )

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Oncology Agents and Immunosuppressants

$27,771,971 for the year ending Jun 03

Endocrine Therapy $4.42M ( 15.93 % )

Chemotherapeutic Agents $5.33M ( 19.18 % )

Immunosuppressants $18.02M ( 64.89 % )

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Respiratory System and Allergies

$60,320,498 for the year ending Jun 03

Remainder $14.05M ( 23.29 % ) Inhaled beta-adrenoceptor agonists - metered dose inhalers $8.09M ( 13.41 % )

Inhaled corticosteroids - breath activated devices $4.40M ( 7.30 % )

haled beta-adrenoceptor agonist and anticholinergic agents - mdi $3.10M ( 5.15 % ) Inhaled beta-adrenoceptor agonists - long acting inhalers $9.99M ( 16.56 % )

Inhaled corticosteroids - metered dose inhalers $20.69M ( 34.30 % )

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Sensory Organs

$8,838,111 for the year ending Jun 03

Ear/Eye Preparations $0.55M ( 6.22 % ) Ear Preparations $0.19M ( 2.15 % )

Eye Preparations $8.10M ( 91.63 % )

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Special Foods

$9,117,426 for the year ending Jun 03

Oral Supplements/Complete Diet (nasogastric/ gastronomy tube feed) $5.79M ( 63.55 % ) Nutrient Modules $0.21M ( 2.30 % ) Gluten Free Foods $0.16M ( 1.72 % )

Foods used for PKU and other inborn errors of metabolism $2.12M ( 23.28 % )

Infant Formulae $0.69M ( 7.54 % ) Remainder $0.15M ( 1.61 % )

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$100,000,000

$120,000,000

$140,000,000

$20,000,000

$40,000,000

$60,000,000

$80,000,000

Alimentary Tract and Metabolism

$0 Blood and Blood Forming Organs Cardiovascular System Dermatologicals ormone Preparations - Systemic excluding Contraceptive Hormones Infections - Agents for Systemic Use Nervous System Oncology Agents and Immunosuppressants Other (GUS,M-SS,SO,SF) Year Ending Jun 2003 Year Ending Jun 1993 Respiratory System and Allergies

Changes in Therapeutic Group Expenditure

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Hormone Prepa

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Therapeutic Group 2 ranked by latest months cost. Top 20

Therapeutic Group 1 Alimentary Tract and Metabolism Blood and Blood Forming Organs Nervous System Nervous System Cardiovascular System Respiratory System and Allergies Alimentary Tract and Metabolism Nervous System Alimentary Tract and Metabolism Therapeutic Group 2 Anti-ulcerants Lipid Modifying Agents Antipsychotics Antidepressants Agents affecting the Renin-Angiotensin system Inhaled corticosteroids - metered dose inhalers Diabetes Management Anti-Epilepsy Drugs Diabetes Current Ranking 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 Ranking Last FYr 1 2 3 4 6 5 8 9 7 10 12 11 13 14 25 16 15 19 22 17 Jun 99 $29,018,532 $23,652,838 $10,515,006 $31,868,040 $26,730,102 $24,946,646 $12,641,985 $13,743,535 $17,206,848 $11,692,010 $13,729,099 $28,253,286 $24,902,091 $7,306,986 $2,613,794 $11,713,497 $7,442,115 $5,549,697 $5,712,088 $4,592,312 Jun 00 $36,076,274 $37,207,267 $23,906,733 $28,603,225 $27,199,511 $19,706,977 $13,990,631 $15,171,503 $18,021,780 $11,968,224 $13,454,449 $23,109,218 $17,545,583 $8,258,004 $3,344,915 $8,955,033 $7,557,108 $6,550,700 $5,697,791 $4,670,665 Jun 01 $42,726,469 $44,772,810 $30,144,865 $24,992,295 $27,224,336 $18,695,585 $16,154,033 $15,977,119 $17,118,611 $15,690,966 $13,671,299 $16,234,941 $15,582,894 $9,629,670 $4,209,326 $7,987,020 $8,432,768 $7,186,365 $6,175,327 $4,659,012 Jun 02 $44,108,946 $40,453,510 $36,673,284 $28,054,262 $21,357,029 $21,905,489 $18,129,334 $17,497,161 $18,585,203 $16,140,248 $14,667,033 $15,365,037 $13,885,554 $10,500,428 $5,952,999 $7,972,065 $8,717,462 $7,729,180 $6,669,986 $7,813,125 Jun 03 $52,189,513 $46,072,135 $40,821,937 $32,740,982 $23,027,544 $20,689,721 $19,428,831 $19,009,181 $18,951,091 $18,020,797 $15,547,437 $14,549,217 $13,770,652 $11,229,678 $9,987,468 $9,231,486 $9,186,469 $8,481,922 $8,098,092 $8,086,529

Oncology Agents and Immunosuppressants Immunosuppressants Nervous System Infections - Agents for Systemic Use Cardiovascular System Nervous System Respiratory System and Allergies Cardiovascular System Alimentary Tract and Metabolism Analgesics Antibacterials Calcium Channel Blockers Antimigraine Preparations Inhaled beta-adrenoceptor agonists long acting inhalers Beta Adrenoceptor Blockers Antidiarrhoeals

Hormone Preparations - Systemic excluding Trophic Hormones Contraceptive Hormones Sensory Organs Respiratory System and Allergies Eye Preparations Inhaled beta-adrenoceptor agonists metered dose inhalers

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Between 21 and 40

Therapeutic Group 1 Infections - Agents for Systemic Use Therapeutic Group 2 Antifungals Current Ranking 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 Ranking Last FYr 20 28 18 23 27 30 21 58 32 33 29 31 35 26 37 34 36 24 38 41 Jun 99 $5,168,367 $1,716,406 $9,323,846 $8,004,686 $3,522,621 $3,091,155 $8,843,867 $1,169,890 $4,444,592 $9,429,039 $3,023,991 $6,675,545 $4,459,797 $15,255,228 $2,729,422 $5,801,277 $3,633,302 $6,975,272 $2,845,152 $4,370,783 Jun 00 $6,160,795 $2,730,232 $8,173,267 $7,925,893 $4,615,898 $3,809,143 $6,876,300 $1,212,941 $4,771,456 $7,274,592 $4,014,170 $7,805,725 $3,332,458 $15,584,787 $3,007,944 $5,469,209 $3,949,351 $7,119,827 $2,500,676 $4,213,914 Jun 01 $7,507,448 $4,108,534 $7,998,076 $6,848,399 $5,254,701 $4,779,823 $7,220,981 $1,341,277 $4,973,598 $5,453,347 $4,909,611 $7,712,053 $3,405,691 $14,164,229 $3,483,620 $5,111,050 $4,117,224 $6,917,491 $3,587,529 $4,044,900 Jun 02 $7,721,583 $5,694,185 $7,752,103 $6,662,428 $5,701,308 $5,310,011 $7,704,576 $1,347,899 $5,135,784 $4,773,055 $5,340,542 $5,266,183 $4,088,416 $5,907,185 $3,953,590 $4,330,779 $4,058,984 $6,632,638 $3,656,380 $3,536,592 Jun 03 $7,930,060 $7,699,420 $7,632,316 $6,725,600 $6,418,012 $5,794,190 $5,662,052 $5,326,454 $5,189,526 $4,740,915 $4,668,532 $4,526,811 $4,424,720 $4,401,188 $4,237,763 $4,160,890 $3,957,211 $3,832,992 $3,461,444 $3,369,180

Hormone Preparations - Systemic excluding Calcium Homeostasis Contraceptive Hormones Genito-Urinary System Dermatologicals Infections - Agents for Systemic Use Special Foods Dermatologicals Contraceptives - hormonal Corticosteroids Topical Antiretrovirals Oral Supplements/Complete Diet (nasogastric/ gastronomy tube feed) Anti-acne Preparations

Oncology Agents and Immunosuppressants Chemotherapeutic Agents Cardiovascular System Musculo-Skeletal System Blood and Blood Forming Organs Cardiovascular System Anti-arrythmics Anti-inflammatory Non Steroidal Drugs (NSAIDs) Antianaemics Alpha Adrenoceptor Blockers

Oncology Agents and Immunosuppressants Endocrine Therapy Respiratory System and Allergies Blood and Blood Forming Organs Nervous System Alimentary Tract and Metabolism Inhaled corticosteroids - breath activated devices Antithrombotic Agents Antiparkinson Agents Vitamins

Hormone Preparations - Systemic excluding Hormone Replacement Therapy Contraceptive Hormones Systemic Blood and Blood Forming Organs Alimentary Tract and Metabolism Fluids and Electrolytes Laxatives

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Between 41 and 60

Therapeutic Group 1 Therapeutic Group 2 Current Ranking 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 Ranking Last FYr 39 42 40 46 44 43 92 50 49 48 51 47 52 45 53 54 62 55 59 56 Jun 99 $3,640,617 $1,746,411 $6,168,384 $2,233,424 $2,639,870 $4,914,351 $336,367 $1,824,402 $1,334,726 $2,070,685 $2,601,562 $2,143,435 $1,462,029 $2,224,471 $1,642,709 $1,973,527 $4,167,261 $1,385,514 $1,337,757 $1,711,576 Jun 00 $3,947,910 $2,171,127 $4,822,005 $2,446,077 $2,404,635 $4,884,660 $305,005 $2,015,829 $1,749,790 $2,033,250 $2,628,855 $2,438,584 $1,552,841 $2,236,766 $1,439,200 $1,922,121 $3,008,579 $1,429,903 $1,293,725 $1,583,410 Jun 01 $4,306,589 $2,533,667 $3,964,462 $1,816,462 $2,397,923 $2,691,528 $297,200 $1,598,342 $1,834,835 $2,121,554 $1,812,126 $2,392,001 $1,725,620 $2,272,092 $1,550,443 $1,867,133 $2,517,091 $1,406,952 $1,296,286 $1,491,850 Jun 02 $3,647,552 $2,832,031 $3,575,853 $2,146,875 $2,390,677 $2,559,367 $481,331 $1,966,757 $2,017,362 $2,066,295 $1,908,636 $2,140,366 $1,866,840 $2,350,609 $1,678,400 $1,647,437 $1,191,896 $1,424,141 $1,301,747 $1,387,937 Jun 03 $3,203,770 $3,104,551 $2,941,638 $2,596,866 $2,496,467 $2,437,845 $2,230,313 $2,181,106 $2,122,395 $2,044,935 $1,964,199 $1,926,202 $1,909,326 $1,887,787 $1,857,077 $1,581,101 $1,451,877 $1,407,247 $1,378,331 $1,308,676

Hormone Preparations - Systemic excluding Sex Hormones Non Contraceptive Contraceptive Hormones Respiratory System and Allergies Respiratory System and Allergies Nervous System Dermatologicals Cardiovascular System Musculo-Skeletal System Inhaled beta-adrenoceptor agonist and anticholinergic agents - mdi Inhaled beta-adrenoceptor agonists breath activated devices Other CNS Agents Psoriasis and Eczema Preparations Nitrates Antirheumatoid Agents

Hormone Preparations - Systemic excluding Corticosteroids and Related Agents for Contraceptive Hormones Systemic Use Special Foods Nervous System Cardiovascular System Respiratory System and Allergies Alimentary Tract and Metabolism Respiratory System and Allergies Alimentary Tract and Metabolism Genito-Urinary System Infections - Agents for Systemic Use Dermatologicals Foods used for PKU and other inborn errors of metabolism Antinausea and Vertigo Agents Diuretics Respiratory devices Digestives including Enzymes Antihistamines Minerals Contraceptives - non-hormonal Antivirals Antibacterials Topical

Hormone Preparations - Systemic excluding Vasopressin Agonists Contraceptive Hormones Respiratory System and Allergies Inhaled anticholinergic agents - metered dose inhalers

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Between 61 and 80

Therapeutic Group 1 Respiratory System and Allergies Alimentary Tract and Metabolism Respiratory System and Allergies Dermatologicals Nervous System Infections - Agents for Systemic Use Therapeutic Group 2 Nasal preparations Metabolic Disorder Agents Inhaled beta-agonist and anticholinergic agents - nebuliser Emollients and Barrier Creams Sedatives and Hypnotics Urinary Tract Infections Current Ranking 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 84 Ranking Last FYr 57 61 60 65 63 67 69 66 70 68 82 64 84 89 74 76 79 72 80 91 Jun 99 $5,092,144 $577,564 $856,232 $1,353,433 $1,479,314 $1,060,316 $571,807 $1,002,966 $184,511 $1,271,932 $1,432,372 $893,187 $379,749 $330,330 $1,018,875 $2,089,242 $573,988 $1,509,605 $375,823 $543,843 Jun 00 $5,327,006 $835,182 $1,233,693 $1,107,005 $1,126,624 $957,792 $581,327 $959,048 $628,478 $1,006,489 $1,459,483 $1,144,799 $450,068 $431,653 $631,963 $2,117,416 $655,638 $1,503,399 $340,018 $521,661 Jun 01 $1,408,704 $994,675 $1,308,514 $997,180 $1,124,658 $958,441 $898,008 $973,432 $730,349 $1,016,352 $727,134 $1,311,390 $544,210 $526,551 $645,117 $656,488 $638,308 $1,486,317 $615,484 $529,379 Jun 02 $1,348,546 $1,220,291 $1,272,722 $1,098,052 $1,186,149 $983,894 $956,830 $987,150 $830,379 $981,344 $587,684 $1,182,557 $560,161 $517,261 $656,495 $646,713 $631,002 $757,386 $605,517 $492,045 Jun 03 $1,283,711 $1,233,476 $1,151,933 $1,151,786 $1,092,099 $1,014,316 $998,821 $978,600 $972,008 $956,165 $923,801 $842,906 $687,415 $670,742 $663,078 $658,222 $649,355 $627,778 $616,801 $581,520

Hormone Preparations - Systemic excluding Thyroid and Antithyroid Agents Contraceptive Hormones Hormone Preparations - Systemic excluding Other Endocrine Agents Contraceptive Hormones Genito-Urinary System Dermatologicals Musculo-Skeletal System Genito-Urinary System Special Foods Blood and Blood Forming Organs Dermatologicals Musculo-Skeletal System Infections - Agents for Systemic Use Alimentary Tract and Metabolism Respiratory System and Allergies Contraceptives - hormonal, Non-interchangeable Antifungals Topical Hyperuricaemia and Antigout Anti-androgen oral contraceptives Infant Formulae Antifibrinolytics, Haemostatics and Local Sclerosants Scalp Preparations Muscle Relaxants Antituberculotics and Antileprotics Antihaemmorrhoidals Anti-allergy Preparations

Hormone Preparations - Systemic excluding Other progestogen preparations Contraceptive Hormones

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Between 81 and 100

Therapeutic Group 1 Alimentary Tract and Metabolism Genito-Urinary System Alimentary Tract and Metabolism Genito-Urinary System Genito-Urinary System Respiratory System and Allergies Sensory Organs Respiratory System and Allergies Cardiovascular System Alimentary Tract and Metabolism Dermatologicals Musculo-Skeletal System Respiratory System and Allergies Respiratory System and Allergies Infections - Agents for Systemic Use Infections - Agents for Systemic Use Cardiovascular System Nervous System Respiratory System and Allergies Respiratory System and Allergies Therapeutic Group 2 Antispasmodics and Other Agents Altering Gut Motility Urinary Agents Mouth and Throat Pregnancy tests - HCG urine Myometrial and vaginal hormone preparations Cystic fibrosis Ear/Eye Preparations Theophylline derviatives Centrally Acting Agents Antacids and Antiflatulants Parasiticidal Preparations Corticosteroids - Injectables Inhaled beta-adrenoceptor agonists nebuliser solutions Inhaled anticholinergic agents nebuliser solutions Antitrichomonal Agents Antimalarials Smoking Cessation Anxiolytics Beta-adrenoceptor agoinists - long acting tablets Nedocromil Current Ranking 80 81 82 83 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 Ranking Last FYr 71 83 78 73 90 85 75 81 88 87 96 93 94 77 98 99 138 86 95 97 $670,261 $395,819 $895,693 $682,005 $331,985 $675,561 Jun 99 $1,435,478 $1,087,673 $697,117 $939,762 $438,905 $480,690 $719,931 $841,499 $565,213 $550,672 $394,965 $768,070 $1,363,285 $1,564,001 $723,890 $275,110 Jun 00 $1,362,910 $575,697 $629,064 $672,180 $445,078 $526,062 $691,957 $747,497 $553,683 $551,462 $407,126 $746,242 $1,011,450 $916,155 $470,484 $305,154 Jun 01 $1,051,563 $559,876 $621,991 $443,007 $463,436 $491,187 $664,340 $663,170 $529,409 $552,833 $393,766 $663,845 $780,216 $764,334 $455,840 $319,420 $0 $553,774 $499,716 $507,059 Jun 02 $773,279 $568,767 $631,714 $680,498 $503,974 $558,347 $650,146 $588,745 $517,329 $525,377 $416,298 $460,175 $457,090 $636,838 $398,380 $344,196 $0 $538,098 $430,941 $409,735 Jun 03 $606,213 $595,605 $592,405 $585,217 $566,338 $554,756 $549,924 $528,691 $509,414 $470,662 $458,634 $451,070 $410,058 $402,225 $378,475 $373,331 $368,520 $366,777 $338,601 $307,586

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Between 101 and 120

Therapeutic Group 1 Various Respiratory System and Allergies Special Foods Genito-Urinary System Sensory Organs Therapeutic Group 2 Agents Used in the Treatment of Poisonings Sodium cromoglycate Nutrient Modules Gynaecological anti-infectives Ear Preparations Current Ranking 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 121 Ranking Last FYr 101 100 104 105 107 102 108 103 109 110 112 111 113 115 116 114 118 117 119 120 Jun 99 $325,750 $1,034,655 $1,121,612 $539,440 $220,261 $312,150 $179,484 $7,307,049 $691,526 $220,083 $112,228 $154,378 $46,250 $40,479 $38,149 $92,166 $16,819 $26,666 $39,830 $41,597 Jun 00 $401,180 $656,057 $220,890 $272,195 $205,527 $288,311 $167,698 $201,531 $144,023 $154,579 $114,183 $144,469 $48,986 $55,207 $48,671 $86,871 $21,296 $32,585 $29,592 $29,375 Jun 01 $547,806 $465,887 $214,973 $249,250 $198,307 $264,076 $170,836 $56,919 $140,442 $136,353 $106,438 $151,028 $62,848 $55,173 $45,480 $74,073 $30,643 $44,071 $35,133 $33,884 Jun 02 $306,968 $334,492 $215,238 $213,480 $199,978 $243,775 $165,246 $225,587 $157,858 $150,440 $98,452 $131,752 $81,039 $62,973 $55,749 $65,877 $39,700 $42,093 $37,993 $26,781 Jun 03 $250,726 $240,885 $209,801 $197,913 $190,095 $183,175 $173,572 $172,682 $156,643 $153,192 $103,102 $96,217 $80,358 $73,472 $58,691 $58,394 $46,776 $40,107 $39,060 $32,585

Hormone Preparations - Systemic excluding Other oestrogen preparations Contraceptive Hormones Dermatologicals Extemporaneously Compounded Preparations and Galenicals Special Foods Dermatologicals Musculo-Skeletal System Respiratory System and Allergies Special Foods Cardiovascular System Dermatologicals Cardiovascular System Dermatologicals Special Foods Nervous System Genito-Urinary System Wart Preparations Extemporaneously Compounded Preparations and Galenicals Gluten Free Foods Antipruritic Preparations Anticholinesterases Beta-adrenoceptor agoinists - oral liquids Oral Supplements Anti-Hypotensive Agents Disinfecting and Cleansing Agents Vasodilators Minor Skin Infections Food Thickeners Anaesthetics Impotence treatment

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Greater than 120

Therapeutic Group 1 Respiratory System and Allergies Cardiovascular System Therapeutic Group 2 Cough preparations Sympathomimetics Current Ranking 120 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 137 135 Ranking Last FYr 106 122 121 123 124 130 127 128 126 129 125 131 132 133 134 $6,730 $11,180 $52,857 $8,182 $11,673 $2,463 $2,481 $0 $79 $29,861 $11,958 $15,463 $1,991 $13,908 $9,481 $58,141 $6,728 $7,159 $2,285 $2,534 $0 $166 $26,565 Jun 99 $210,369 $17,954 $29,913 $38,502 $12,185 Jun 00 $242,664 $18,690 $20,746 $29,473 $17,529 Jun 01 $221,875 $24,630 $22,164 $24,025 $16,702 $7,422 $12,543 $7,532 $23,967 $8,377 $47,678 $6,380 $4,547 $2,422 $1,764 $54 $90 $19,254 $38 $403 Jun 02 $207,873 $24,528 $25,231 $21,218 $18,972 $6,232 $13,114 $7,906 $15,452 $6,576 $17,097 $5,345 $4,464 $2,082 $1,301 Jun 03 $35,219 $27,660 $24,321 $19,368 $14,108 $12,410 $9,808 $9,114 $7,681 $5,177 $4,661 $4,392 $2,563 $1,727 $1,118 $84 $51 $5

Hormone Preparations - Systemic excluding Anabolic Agents Contraceptive Hormones Infections - Agents for Systemic Use Special Foods Special Foods Respiratory System and Allergies Various Respiratory System and Allergies Dermatologicals Dermatologicals Dermatologicals Respiratory System and Allergies Various Musculo-Skeletal System Dermatologicals Cardiovascular System Respiratory System and Allergies Anthelmintics Multi Vitamin Supplements Protein Supplements, Formulae Used for PKU and other Inborn Errors of Metabolism Beta-adrenoceptor agoinists - injection Preparations Used in the Treatment of Drug Dependancy Inhaled corticosteroids - metered dose inhalers with spacers Sunscreens Other Skin Preparations Dusting Powders Inhaled corticosteroids - nebuliser solution Detection of Substances in Urine Enzymes Antivirals Topical Adrenergic Neurone Blockers Other broncholdilators